What is Oral Mucositis?

​Oral mucositis is a painful inflammation of the lining of the mouth and throat (oral mucosa) and is one of the most common complications of radiation and chemotherapy cancer treatments. It is extremely painful and debilitating for patients and has a serious impact on their Quality of Life. (1,2)

 

Oral mucositis can manifest as oral mucosal atrophy, erythema, erosion, and ulceration or as a combination of these manifestations.(2) Severe cases of OM may interrupt a patient's cancer treatment schedule if not properly addressed.

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What are the signs of Oral Mucositis? (3)

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Complications of Oral Mucositis

Oral Mucositis can lead to complications, including: (3)(4)

  • Severe pain and inflammation

  • Increased risk of infections

  • Malnutrition as a result of restricted oral intake

  • Dehydration

  • Difficulty speaking

  • Increased use of prescription opioids

  • Interruption of therapy

  • Increased length of hospitalisation and overall cost of treatment

References:  1. Singh V, Singh AK. Oral mucositis. Natl J Maxillofac Surg. 2020 Jul-Dec;11(2):159-168. doi: 10.4103/njms.NJMS_10_20. Epub 2020 Dec 16. PMID: 33897175; PMCID: PMC8051654. [Available from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051654] Accessed August 2022 2. S.S. Shetty, M. Maruthi and V. Dhara et al. Oral Mucositis: Current knowledge and future directions [Available from: https://linkinghub.elsevier.com/retrieve/pii/S0011502921001760] Accessed August 2022 3. Oral Cancer Foundation. Online [Available from: https://oralcancerfoundation.org/complications/mucositis/] Accessed August 2022 4. Oral mucositis. The American Academy of Oral Medicine. [Available from: https://www.aaom.com/index.php?option=com_content&view=article&id=149:oral-mucositis&catid=22:patient-condition-information&Itemid=120. January 22, 2015.] Accessed August 2022

MAT-GELX OS-UK-000021  Date of Preparation: August 2022